Are You or Your Patients Interested in Clinical Trials?
Clinical trials are structured and measured research studies that help determine the safety and effectiveness of:
- Ground-breaking medical tests
- Innovative new treatments
- Pioneering medical devices
- Newly discovered medications
Clinical trials help determine the effectiveness in screening for, diagnosing, treating, or preventing a certain disease or condition and are a critical part of the ongoing work of researchers to discover new medical therapies and improve existing ones. These studies add to existing medical knowledge and provide reliable data to assist in healthcare decision-making and guideline creation.
Health Care Professionals Help Get the Word Out
People of all walks of life take part in clinical trials for various reasons and often it is their physician or health care professional that helps connect the patient with an appropriate clinical trial. Great effort is made to assure that clinical research trials are safely administered and closely monitored to ensure the wellbeing of participants.
Here is a resource of links to clinical trials:
Abbott Laboratories: https://www.abbott.com/policies/clinical-trials.html
Amgen is evaluating Romosozumab in Children and Adolescents With Osteogenesis Imperfecta.
Amryt Pharma: https://clinicaltrials.gov/study/NCT05164341
Note: Amryt Pharma is currently recruiting for a phase 3, double-blind, placebo-controlled study in subjects 12 years and older with a clinical diagnosis of Familial Partial Lipodystrophy (FPLD) who have failed to achieve adequate metabolic control using standard treatments. The study will evaluate the safety and efficacy of daily subcutaneous metreleptin. Eligible subjects will receive metreleptin or placebo treatment at a ratio of 1:1 for 12 months.
The AstraZeneca Clinical Trials Database provides patients, caregivers, doctors, researchers and the public with information about AstraZeneca’s sponsored clinical trials and what it means to participate in one.
Bayer: Welcome to Bayer Clinical Trials
The Bayer Clinical Trials Registry and Results Database website contains information on clinical trials sponsored by Bayer, and is provided for patients and healthcare professionals to increase the transparency of Bayer's clinical research.
Boehringer Ingelheim: https://medinfo.boehringer-ingelheim.com/us/research-development/clinical-trials
Use the clinical trials search to access BI trials for specific health conditions.
GRADIENT - Open for enrollment https://clinicaltrials.gov/ct2/show/NCT04308590
This is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy, and safety of relacorilant to treat hypercortisolism in patients with cortisol-secreting adrenal adenoma or hyperplasia associated with diabetes mellitus/ impaired glucose tolerance and/or uncontrolled systolic hypertension.
CATALYST - Open for enrollment https://www.clinicaltrials.gov/study/NCT05772169?term=corcept&rank=6
This is a Phase 4 study with 2 parts: Part 1 (Prevalence Phase) is non-interventional and will assess the prevalence of hypercortisolism in a population with difficult to control type 2 diabetes (T2D) (hemoglobin A1c ≥7.5%) despite receiving standard-of-care therapies. Part 2 (Treatment Phase) is a randomized, prospective, placebo-controlled, double-blind multi-center trial that will assess the safety and efficacy of mifepristone treatment in patients with hypercortisolism who have difficult to control T2D despite receiving standard of care therapies.
The GO research studies are evaluating the effectiveness and safety of an investigational medication, batoclimab, that targets the immune system in patients with moderate-to-severe TED. The results of these studies will provide more information on batoclimab and whether it could work to treat TED and improve the quality of life for patients.
Lilly’s new Trial Match feature allows you to search for clinical trials that may be the best fit for you or a loved one. Simply answer a few questions to find which Lilly trials may be the best match.
Novo Nordisk: NN Trials (novotrials.com)
Information about all clinical trials from Novo Nordisk.
The PETITE Trial is looking at the safety and pharmacokinetics/dynamics of teplizumab in children with Stage 2 T1D under 8 years of age.
Vertex is investigating therapies aimed at replacing the insulin-producing cells that have been destroyed in people with T1D. To learn more about Vertex T1D clinical trials, go to: t1dtstudy.com.