Ozempic feet are characterized by sagging skin and reduced fat padding in the feet, which can occur with rapid weight loss. AACE President Scott D. Isaacs, MD, FACP, FACE, and AACE member Karl Nadolsky, DO, FACE, DABOM, explain that this side effect may occur with any significant and rapid weight loss. In an article by Health.com, they emphasize the importance of gradual weight loss, proper foot care, and ongoing medical oversight to manage related risks.