AACE members Shailendra B. Patel, BM, ChB, DPhil, and Kathleen L. Wyne, MD, PhD, provide insights on the new AACE Clinical Practice Guideline for the Pharmacologic Management of Adults with Dyslipidemia. Based on the GRADE evidence-rating system, the guideline helps clinicians make informed treatment decisions by focusing on patient-important outcomes. They highlight that while newer cholesterol-lowering medications may offer benefits, their impact on major heart-related outcomes is limited, and certain risk assessment tests provide only small improvements in predicting cardiovascular disease. Read the full article on Medscape to explore these expert perspectives and key recommendations.