Disease State Resources

New 2020 clinical practice guidelines aim to provide evidence-based information about the diagnosis, evaluation, and treatment of postmenopausal osteoporosis for endocrinologists, physicians in general, regulatory bodies, health-related organizations, and interested laypersons.

This consensus document will present recommendations for the use of MHT for the relief of menopausal symptoms. It will consider the possible role of MHT in the prevention of chronic disorders associated with estrogen deficiency. Moreover, it will assess the benefit-versus-risk profile of MHT, including our current understanding of the effects of MHT on multiple organ systems.

The purpose of these guidelines is to present a framework for the evaluation, treatment, and follow-up of the patient—indeed, of the couple—who presents with sexual dysfunction. The conventional focus on male erectile dysfunction is incomplete because whenever a man experiences erectile difficulties, his wife or sexual partner suffers as well.

In these clinical practice guidelines, specific recommendations are made for determining the most effective methods of diagnosing and treating hypogonadism in adult male patients.

The purpose of this document is to provide guidelines for the diagnosis and treatment of hyperandrogenic disorders in women. These may range from simple hirsutism, without clearly demonstrable biochemical features of hyperandrogenism, to frank virilization.

This updated guideline provides evidence-based recommendations regarding the identification, screening, assessment, diagnosis, and treatment for a range of individuals with various causes of adult growth-hormone deficiency (GHD) and patients with childhood-onset GHD transitioning to adult care.

Acromegaly is a disorder characterized by growth hormone (GH) hypersecretion, multisystem-associated morbidities, and increased mortality. In 2004, the American Association of Clinical Endocrinologists (AACE) published medical guidelines for the clinical management of acromegaly (1 [“evidence level” or EL 4]).

The incidence of adrenal incidentaloma, a term coined in reference to the phenomenon of detecting an otherwise unsuspected adrenal mass on radiologic imaging, has been increasing and now approaches the 8.7% incidence reported in autopsy series.

Growth-hormone deficiency (GHD) in adulthood associated with hypothalamic-pituitary dysfunction is now widely accepted as a distinct clinical syndrome, and is linked to a substantial number of metabolic abnormalities, many of which can be ameliorated with GH replacement therapy.

These AACE/ACE evidence-based clinical practice guidelines address key aspects of obesity care: screening, diagnosis, clinical evaluation, treatment options, therapy selection, and treatment goals.

The American Association of Clinical Endocrinologists (AACE) and The Obesity Society (TOS) are professional organizations dedicated to improve the lives of patients with endocrine and metabolic disorders.

Cosponsored by American Association of Clinical Endocrinologists/American College of Endocrinology, The Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists

This algorithm for the comprehensive management of persons with type 2 diabetes (T2D) was developed to provide clinicians with a practical guide that considers the whole patient, his or her spectrum of risks and complications, and evidence-based approaches to treatment.

These 2015 clinical practice guidelines (CPGs) for developing a diabetes mellitus (DM) comprehensive care plan are an update of the 2011 American Association of Clinical Endocrinologists (AACE) Medical Guidelines for Clinical Practice for Developing a Diabetes Mellitus Comprehensive Care Plan.

This document was prepared as a collaborative effort between the American Association of Clinical Endocrinologists (AACE), American College of Endocrinology (ACE) and Associazione Medici Endocrinologi (AME). These guidelines cover diagnostic and therapeutic aspects of thyroid nodular disease but not thyroid cancer management.

Hypothyroidism has multiple etiologies and manifestations. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions. This paper describes evidence-based clinical guidelines for the clinical management of hypothyroidism in ambulatory patients.

Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference.

Clinical practice guideline (CPG), clinical practice algorithm (CPA), and clinical checklist (CC, collectively CPGAC) development is a high priority of the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE).

This clinical practice guideline is a practical tool that endocrinologists, other health care professionals, health-related organizations, and regulatory bodies can use to reduce the risks and consequences of dyslipidemia.

These guidelines use the best evidence, taking into consideration the economic impact of the disease and the need for efficient and effective evaluation and treatment of postmenopausal women with osteoporosis.

The incidence of adrenal incidentaloma, a term coined in reference to the phenomenon of detecting an otherwise unsuspected adrenal mass on radiologic imaging, has been increasing and now approaches the 8.7% incidence reported in autopsy series (1 [evidence level or EL 3], 2 [EL 3]).