Should Older Men with Age-Related Decline in Testosterone levels Receive Testosterone Replacement?
This session is LIVE online: May 20, 2020 at 8:30 pm EDT!
Shalender Bhasin, MD
Dr. Shalender Bhasin is the recipient of the 2020 AACE Frontier in Science Award, will discuss the findings of his ground-breaking clinical trials examining the role of testosterone therapy in aging, sarcopenia, and atherosclerosis.
- Evaluate the health consequences of age-related decline in testosterone levels.
- Recognize the potential benefits and risks of testosterone replacement in older men with age-related decline.
- Synthesize the data from the randomized clinical trials of testosterone to guide shared decision to treat or not to treat older men with testosterone replacement therapy.
Dr. Bhasin is a Professor of Medicine at Harvard Medical School, and Director of the Research Program in Men's Health, Aging and Metabolism, and Director of the Boston Claude D. Pepper Aging Research Center at Brigham and Women's hospital.
Dr. Bhasin is a translational investigator, whose investigations have been notable for their bold study design, innovation, and their enduring impact in bringing resolution to some of the most controversial issues in reproductive endocrinology and in spawning a whole new biotechnology industry around the clinical applications of androgens and selective androgen receptor modulators (SARMs). Dr. Bhasin’s discoveries include characterization of testosterone’s biologic effects, its dose-response relationships in men and women, and its potential benefits and adverse effects. His research provided the first demonstration that testosterone increases muscle mass and strength, elucidated the mechanisms by which testosterone increases muscle mass and stimulates erythropoiesis, and clarified the role of steroid 5α-reductase type 2 in men.
He chaired the Endocrine Society's panel that developed the guidelines for testosterone replacement therapy in hypogonadal men. Dr. Bhasin has led important randomized trials of testosterone in hypogonadal men, in older men with age related decline in testosterone, and in men and women with sarcopenia and functional limitations. These RCTs have clarified the benefits and risks of testosterone and formed the basis of the testosterone guideline, which he has led since 2005 through its 3 updates. He has led the efforts to generate harmonized, population-based references ranges for testosterone in men, characterized testosterone’s binding to SHBG and described a new model for estimation of free testosterone. He has served as an Associate Editor of the JCEM and the Journal of Andrology, the Chair of the Clinical Guidelines and of the Expert Panel that developed guidelines for Testosterone Therapy, and Chair of ABIM Endocrinology and Metabolism Subspecialty Board.
Accreditation and Credits
The American Association of Clinical Endocrinologists (AACE) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The American Association of Clinical Endocrinologists (AACE) designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Maintenance of Certification
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 MOC point in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Only those who receive a passing score will be eligible for MOC credit. Please allow two weeks for MOC points to appear within your account on the ABIM website. Participation information will be shared with the American Board of Internal Medicine (ABIM) through the Accreditation Council for Continuing Medical Education (ACCME) Program and Activity Reporting System (PARS).