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Thyroid Awareness Month 2003

TSH Level Explanation

Below is further explanation on AACE position on changing the TSH scores:

Until recently, physicians accepted the normal TSH range of 0.5 to 5.0 mIU/L. Recent data suggest that normal serum TSH levels may have a narrower range. For example, the National Academy of Clinical Biochemistry (NACB) guidelines believes that a sustained TSH level above 2.5 mIU/L might not be normal and that current TSH upper limits of >4 mIU/L are likely skewed by the inclusion of individuals with occult thyroid deficiency. The NACB guidelines were published in their entirety in the January issue of the Thyroid.

Last year an AACE task force reviewed available data and current trends in practice, and updated the AACE Guidelines for Clinical Practice for the Evaluation and Treatment of Hyperthyroidism and Hypothyroidism published in the November/December 2002 issue of Endocrine Practice. The task force also suggested that in patients on thyroxine replacement therapy, which is stated in the guidelines as "The target TSH level should be between 0.3 and 3.0 uIU/mL". By inference, any patient with TSH outside this range has an "abnormal" level which should be carefully followed but not necessarily treated. Some authors, however, treat marginally abnormal TSH when coupled with positive TPO titers because of high conversion rates to clinical hypothyroidism. This area remains very controversial but other endocrine organizations such as The Endocrine Society and the American Thyroid Association are in agreement with the AACE position. This point of view was presented, along with the new AACE guidelines, to the public in January 2003 during AACE's annual Thyroid Awareness Month campaign.

 

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Thyroid Awareness Month is supported through an unrestricted grant from Abbott Laboratories.
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